Archive for March, 2023

Obesity patients left struggling after NHS cuts

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An obesity scheme in Rotherham which was successful in helping people lose weight has has received criticism for going private after losing their NHS funding.

Rotherham is one of the country’s obesity hotspots where two in every three adults is classified as either overweight or heavier.

Despite the scale of the obesity problem, NHS treatment for the most serious patients is no longer available in the South Yorkshire town.

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Obesity Management – Dr.Ravi Sankar Endocrinologist MRCP(UK) CCT – GIM (UK)

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Obesity Management – Dr.Ravi Sankar Endocrinologist MRCP(UK) CCT – GIM (UK)

Obesity
————-
Weight Status Body Mass Index (BMI)
Underweight less than 18.5
Normal or Healthy Weight 18.5–24.9
Overweight greater than or equal to 25–29.9
Class I Obesity 30–34.9
Class II Obesity 35–39.9
Class III Obesity greater than or equal to 40
Morbid obesity is diagnosed when the patients meet greater than or equal to 1 of the following criteria:
greater than or equal to100 pounds over the ideal body weight
BMI greater than or equal to 40
BMI greater than or equal to 35 and health conditions related to obesity (e.g., hypertension, diabetes)

Treatment
—————–
First-line: lifestyle modifications
Dietary changes: calorie restriction, healthy foods (e.g., fruit/vegetables, protein-rich, unsaturated fats, sodium-restricted)
Physical activity: minimum of 30 minutes moderate exercise per day (2.5 hours per week) , which increases insulin sensitivity, lowers blood pressure, and promotes weight loss
Medical therapy: treat hypertension (e.g., ACE inhibitors), diabetes mellitus, and dyslipidemia (e.g., with statins)
Bariatric surgery: if BMI ≥ 40 and no success with dietary and lifestyle changes
Sleeve gastrectomy (most common): large part of the greater curvature is removed, so that the remaining stomach resembles a sleeve
Roux-en-Y gastric bypass (2nd most common): Roux-en-Y

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Pharmacology – HYPERTENSION & ANTIHYPERTENSIVES (MADE EASY)

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Pharmacology - HYPERTENSION & ANTIHYPERTENSIVES (MADE EASY)

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Antihypertensives are a class of drugs that are used to treat hypertension. Antihypertensive therapy seeks to prevent the complications of high blood pressure such as heart attack and stroke. This pharmacology lecture covers topics such as pathophysiology of hypertension, regulation of blood pressure, cardiac output, systemic vascular resistance, baroreceptors, alpha & beta receptors, vasoconstriction, vasodilation, renin-angiotensin-aldosterone system, bradykinin, nitric oxide. Mechanism of action of antihypertensive drugs and their side effects; adrenergic antagonists; alpha & beta blockers, centrally acting adrenergic agents, dihydropyridine & nondihydropyridine calcium channel blockers, loop, thiazide, potassium-sparing diuretics, renin inhibitors, angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor type 1 blockers (ARBs), endothelin receptor antagonist, dopamine-1 receptor agonist, peripheral vasodilators. Drugs mentioned include; Doxazosin, Prazosin, Clonidine, Methyldopa, Amlodipine, Felodipine, Nicardipine, Nifedipine, Diltiazem, Verapamil, Furosemide, Hydrochlorothiazide, Triamterene, Spironolactone, Aliskiren, Benazepril, Captopril, Enalapril, Lisinopril, Quinapril, Ramipril, Candesartan, Irbesartan, Losartan, Olmesartan, Valsartan, Bosentan, Fenoldopam, Sodium Nitroprusside, Nitroglycerin, Hydralazine, and Minoxidil.

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0:00 Pathophysiology of hypertension
2:55 Alpha-1 blockers
3:10 Beta blockers
4:01 Centrally-acting adrenergic drugs
4:49 Calcium channel blockers
7:27 Diuretics
8:57 Inhibitors of renin-angiotensin-aldosterone system
12:25 Miscellaneous antihypertensives

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